Finale 2014 trial manual#
Finale 2014 trial professional#

Treatment with bisphosphonate or denosumab within 12 weeks before randomisation.

Severe or uncontrolled concurrent disease, infection or co-morbidity.

Radiation therapy within 12 weeks before randomisation.

Prior chemotherapy or immunotherapy for prostate cancer.

Use of estrogens or 5-О± reductase inhibitors or AR inhibitors.

Prior treatment with: second generation androgen receptor (AR) inhibitors, other investigational AR inhibitors, or CYP17 enzyme inhibitor.

Acute toxicities of prior treatments and procedures not resolved to grade в‰¤ 1 or baseline before randomisation.

History of metastatic disease at any time or presence of detectable metastases.

Sexually active patients, unless surgically sterile, must agree to use condoms as an effective barrier method and refrain from sperm donation during the study treatment and for 3 months after the end of the study treatment.

Screening values of serum alanine aminotransferase (ALT) and/or aspartate transaminase (AST) в‰¤ 2.5 x upper limit of normal (ULN), total bilirubin в‰¤ 1.5 x ULN, creatinine в‰¤ 2.0 x ULN.

Blood counts at screening: haemoglobin в‰Ґ 9.0 g/dl,absolute neutrophil count в‰Ґ 1500/Вµl, platelet count в‰Ґ 100,000/Вµl.

Eastern Cooperative Oncology Group (ECOG) performance status of 0-1.

Prostate-specific Antigen (PSA) doubling time of в‰¤ 10 months and PSA > 2ng/ml.

Castration-resistant prostate cancer (CRPC) with castrate level of serum testosterone.

Histologically or cytologically confirmed adenocarcinoma of prostate without neuroendocrine differentiation or small cell features.

Why Should I Register and Submit Results?.

Nevertheless, we certainly recommend Finale for composing music. Needless to say, beginners would have a difficult time working with this software. The application didn't freeze or crash during our tests and comes with a complete user guide. However, Finale uses a massive amount of system memory, which is to be expected in such a major audio suite. The program's response time is generally good, although sometimes it needs a few seconds to apply major changes or load a document. Also, hotkeys are assigned to each major function in Finale. So, you can add chords, repeats, lyrics, tempo marking and dynamics, articulations, slurs, hairpins, Garritan sounds from an extensive database, and more. Select a note type and click a particular section to input it (don't worry you can listen to that specific key after you place it on the sheet).ДЇurthermore, you can make changes by editing using a simple entry (via the Simple Entry palette or by using the keyboard) or by entering multiple rhythmically independent lines of music on the same staff.

You can enter music by using the mouse and keyboard or by transcribing a live performance. When you run the setup wizard, you must first select an ensemble and a document style to work with, and personalize the layout, after which you can select instruments from a particular category, then set the title, credits, copyright, key signature, time signature, tempo and pickup measure.

Finale 2014 trial manual#

When you first initiate the program, you are welcomed by a screen in which you can create new sounds by entering the setup or exercise wizard, start a new project from a default document or from a template.Д«ut you can also view quick start videos, consult the user manual and take a look at the tutorial guide.

Finale 2014 trial professional#

Finale is a powerful solution bent on assisting you in composing music in a professional manner.